competitive price 1-(5-Bromo-2-Methoxyphenyl)-Adamantane for Adapalene CAS NO.104224-63-7

1-(5-Bromo-2-Methoxyphenyl)-Adamantane CAS:104224-63-7 

Name		1-(5-Bromo-2-methoxy-phenyl)adamantane
Synonyms		1-(5-Bromo-2-methoxyphenyl)-tricyclo[3.3.1.1(3,7)]decane; 2-(1-Adamantyl)-4-bromo-anisole
Molecular Structure
Molecular Formula		C17H21BrO
Molecular Weight		321.25
CAS Registry Number		104224-63-7

HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture.

With about ten years of business experiences on the marketing & distribution, thinkchem specializes in exporting pharmaceuticals, veterinary drugs, feed additives, intermediates, fine chemicals, plants extracts, pesticides, food & nutrition additives.

Thinkchem is good at offering excellent outsourcing services to overseas customers as well as laboratory support.

Custom manufacture

Thinkchem is good at offering contract manufacture and custom synthesis under confidential agreement timely and effectively, and providing sales service from grams ,kilograms to multi-tons particularly for pharmaceuticals and their intermediates discovery and development. Thinkchem is equipped with modern lab apparatus including HPLC, GC. TLC AND NMR, motivated by a team of highly qualified personnel using these equipments.

Staff

Thinkchem is composed of chemical technicians, analytical chemists, organic chemists, and chemical engineers educated in leading universities in china. Our staff is supported by a group of consultants from academia with expertise in chemical synthesis and analytical chemistry.

Adapalene Intermediates
1-(5-Bromo-2-Methoxyphenyl)-Adamantane CAS:104224-63-7 
Ethyl 4-(Ethoxycarbonyl)piperidine-1-Acetate CAS:1838-39-7

Items                     Specifications                 Results

Appearance:       yellow to white crystalline powder       Complies

Identification:                IR spectrum                   Complies

Loss on drying:               0.5%max.                     0.1%

Water(KF):                   0.5%max.                     0.1%

Residue on ignition:           0.1%max.                     0.02%

Specific rotation:             +82⁰~+89⁰                               +86.9⁰

Residual solvents:

Methanol:                  300ppm max.                  25ppm

Ethanol:                   500ppm max.                   Undetected

Acetone:                   500ppm max.                  4ppm

Dichloromethane:           600ppm max.                  126ppm

Ethyl acetate:               500ppm max.                 Undetected

Related substance(HPLC):

Compound Ⅴ:               0.2%max.                   Undetected

Iso:                         0.2%max.                   Undetected

Dipyrrolidine D:              0.5%max.                     0.45%

Impurity A at RRt~0.21:       1.7%max.                     1.06 %

Impurity B at RRt~0.55:       0.6%max.                     0.23%

Impurity C at RRt~1.26:       0.5%max.                    Undetected

Any other unidentified:        0.2%max.                     Undetected

Total impurities:              2.5%max.                     1.45%

Assay(titration):              99.0%min.                     99.6%

(calculated on dried basis)

Morpholine:                  0.2%max.                    Undetected

Rocuronium Bromide[CAS:119302-91-9] 

2a,3a,16a,17a-Diepoxy-17b-acetoxy-5a-androstane[CAS:50588-22-2]

(2a,3a,5a,16b,17b)-2,3-Epoxy-16-(1-pyrrolidinyl)androstan-17-ol[CAS:119302-19-1]

(2b,3a,5a,16b,17b)-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane-3,17-diol[CAS:119302-20-4]

(2b,3a,5a,16b,17b)-17-acetoxy-3-hydroxy-2-(4-morpholinyl)-16-(1-pyrrolidinyl)androstane[CAS:119302-24-8]

1. Well-trained professional sales team dedicated to source, audit and export.

2. Well-trained R & D team equipped with new knowledge, new ideas and new insights to support product development and innovation.

3. Well-established partnership with major pharmaceutical and chemical companies in china.

4. Wide range of products and efficient regulatory documentation offered to customers.